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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL459142
Molecular formula	C25H31N7O3
IUPAC name	6-[2-(4,5-dihydro-1H-imidazol-2-ylamino)ethylamino]-3-[(4-ethylphenyl)methyl]-1-[(4-methoxyphenyl)methyl]-1,3,5-triazine-2,4-dione
Molecular weight	477.569
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	1.9
Synonyms	6-{[2-(4,5-dihydro-1H-imidazol-2-ylamino)ethyl]amino}-3-[(4-ethylphenyl)methyl]-1-[(4-methoxyphenyl)methyl]-1,2,3,4-tetrahydro-1,3,5-triazine-2,4-dione BDBM26337
Inchi Key	IQQIHJNOLKQKPV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31N7O3/c1-3-18-4-6-19(7-5-18)17-32-24(33)30-23(29-15-14-28-22-26-12-13-27-22)31(25(32)34)16-20-8-10-21(35-2)11-9-20/h4-11H,3,12-17H2,1-2H3,(H2,26,27,28)(H,29,30,33)
PubChem CID	25138122
ChEMBL	CHEMBL459142
IUPHAR	N/A
BindingDB	26337
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
139520	Prokineticin receptor 1	Q8TCW9	PROKR1	Homo sapiens (Human)	393
139521	Prokineticin receptor 2	Q8NFJ6	PROKR2	Homo sapiens (Human)	384

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