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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3260506
Molecular formula	C23H18Cl2FN3O2
IUPAC name	ethyl 3-(2-chloro-6-fluorophenyl)-2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]propanoate
Molecular weight	458.314
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	5.5
Synonyms	Oprea1_475433 AKOS005080981 MCULE-2919223527 SCHEMBL1246675 BDBM50013994 ethyl 3-(2-chloro-6-fluorophenyl)-2-[3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]propanoate 12N-708 MolPort-002-857-518 AC1N8TZT KS-000031DH 477860-54-1 [ Show all ]
Inchi Key	INWVFZRLLMCXOO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H18Cl2FN3O2/c1-2-31-23(30)17(12-16-19(25)4-3-5-20(16)26)21-10-11-27-22-18(13-28-29(21)22)14-6-8-15(24)9-7-14/h3-11,13,17H,2,12H2,1H3
PubChem CID	4400062
ChEMBL	CHEMBL3260506
IUPHAR	N/A
BindingDB	50013994
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
137689	Glucose-dependent insulinotropic receptor	Q7TQP3	Gpr119	Mus musculus (Mouse)	335
137690	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335

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