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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1172940
Molecular formula	C28H24FN5O3
IUPAC name	N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-(4-methylpiperazin-1-yl)phenyl]pyridin-2-yl]furan-2-carboxamide
Molecular weight	497.53
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	4.7
Synonyms	N-{3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-(4-methylpiperazin-1-yl)phenyl]pyridin-2-yl}furan-2-carboxamide SCHEMBL13802113 BDBM50322301
Inchi Key	HKKZYFOWBDIXIQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H24FN5O3/c1-33-9-11-34(12-10-33)20-5-2-4-18(14-20)22-16-24(21-8-7-19(29)15-25(21)35)31-27(23(22)17-30)32-28(36)26-6-3-13-37-26/h2-8,13-16,35H,9-12H2,1H3,(H,31,32,36)
PubChem CID	136016518
ChEMBL	CHEMBL1172940
IUPHAR	N/A
BindingDB	50322301
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
560927	KiSS-1 receptor	Q969F8	KISS1R	Homo sapiens (Human)	398

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