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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000178049
Molecular formula	C11H7F2NO3
IUPAC name	1-[4-(difluoromethoxy)phenyl]pyrrole-2,5-dione
Molecular weight	239.178
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.0
Synonyms	1-[4-(difluoromethoxy)phenyl]pyrrole-2,5-dione BIM-0002866.P001 MCULE-2526262106 ST50272509 SCHEMBL8678075 ZINC459275 1-(4-Difluoromethoxy-phenyl)-pyrrole-2,5-dione 1-[4-(difluoromethoxy)phenyl]-3-pyrroline-2,5-quinone BAS 03571070 F1065-0202 SR-01000367201 1-[4-[bis(fluoranyl)methoxy]phenyl]pyrrole-2,5-dione CB04567 MLS000559359 STL019559 AC1LHFH4 CHEMBL1570845 1-[4-(difluoromethoxy)phenyl]-1H-pyrrole-2,5-dione 1-[4-(difluoromethoxy)phenyl]azoline-2,5-dione BDBM79996 HMS2525D03 SR-01000367201-1 68255-65-2 CBMicro_002628 MolPort-000-689-379 Z56802708 1-(4-(difluoromethoxy)phenyl)-1H-pyrrole-2,5-dione 1-[4-(difluoromethoxy)phenyl]-2,5-dihydro-1H-pyrrole-2,5-dione AKOS000569374 cid_886511 SMSF0018580 [ Show all ]
Inchi Key	HJLVVPXYRWXDKO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H7F2NO3/c12-11(13)17-8-3-1-7(2-4-8)14-9(15)5-6-10(14)16/h1-6,11H
PubChem CID	886511
ChEMBL	CHEMBL1570845
IUPHAR	N/A
BindingDB	79996
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
116529	C-C chemokine receptor type 6	P51684	CCR6	Homo sapiens (Human)	374
116528	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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