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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL198387
Molecular formula	C29H34F3N7O3
IUPAC name	4-[[9-tert-butyl-2-oxo-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[5.5]undecan-1-yl]methyl]-N-(2H-tetrazol-5-yl)benzamide
Molecular weight	585.632
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	5.9
Synonyms	706812-04-6 KB-74945 Benzamide, 4-[[9-(1,1-dimethylethyl)-2-oxo-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[5.5]undec-1-yl]methyl]-N-2H-tetrazol-5-yl- trans-4-[9-tert-Butyl-2-oxo-3-(4-trifluoromethoxy-phenyl)-1,3-diaza-spiro[5.5]undec-1-ylmethyl]-N-(1H-tetrazol-5-yl)-benzamide 4-[9-tert-Butyl-2-oxo-3-(4-trifluoromethoxy-phenyl)-1,3-diaza-spiro[5.5]undec-1-ylmethyl]-N-(1H-tetrazol-5-yl)-benzamide BDBM50171819 SCHEMBL2665867 Benzamide,4-[[9-(1,1-dimethylethyl)-2-oxo-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[5.5]undec-1-yl]methyl]-N-2H-tetrazol-5-yl- ZINC6718454 CHEMBL502203 BDBM50244078 SCHEMBL5946516 4-({9-t-butyl-2-oxo-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[5.5]undec-1-yl}methyl)-N-(2h-tetrazol-5-yl)benzamide [ Show all ]
Inchi Key	FVDONABKZHMTCY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H34F3N7O3/c1-27(2,3)21-12-14-28(15-13-21)16-17-38(22-8-10-23(11-9-22)42-29(30,31)32)26(41)39(28)18-19-4-6-20(7-5-19)24(40)33-25-34-36-37-35-25/h4-11,21H,12-18H2,1-3H3,(H2,33,34,35,36,37,40)
PubChem CID	10054055
ChEMBL	CHEMBL198387
IUPHAR	N/A
BindingDB	50171819
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
88004	Gastric inhibitory polypeptide receptor	P48546	GIPR	Homo sapiens (Human)	466
88005	Glucagon receptor	P47871	GCGR	Homo sapiens (Human)	477
88006	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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