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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL327231
Molecular formula	C27H33FN8O2
IUPAC name	4-[3-[4-[4-fluoro-2-(1,3-oxazol-2-yl)phenyl]piperazin-1-yl]propylamino]-N,N,1,3-tetramethylpyrazolo[3,4-b]pyridine-5-carboxamide
Molecular weight	520.613
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	3.4
Synonyms	N,N,1,3-Tetramethyl-4-[3-[4-[2-(oxazol-2-yl)-4-fluorophenyl]piperazino]propylamino]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Inchi Key	FPZDPICFUSMQDJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H33FN8O2/c1-18-23-24(21(27(37)33(2)3)17-31-25(23)34(4)32-18)29-8-5-10-35-11-13-36(14-12-35)22-7-6-19(28)16-20(22)26-30-9-15-38-26/h6-7,9,15-17H,5,8,10-14H2,1-4H3,(H,29,31)
PubChem CID	10506159
ChEMBL	CHEMBL327231
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
84497	Alpha-1A adrenergic receptor	O02824	ADRA1A	Oryctolagus cuniculus (Rabbit)	466
84498	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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