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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	633283-39-3
Molecular formula	C17H16ClN3OS
IUPAC name	3-amino-N-[(4-chlorophenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
Molecular weight	345.845
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.6
Synonyms	2-Furoyl-LIGRLO-amide trifluoroacetate salt A3274/0139289 CTK5B8654 MLS002474501 VU 10010 3-amino-N-(4-chlorobenzyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide B7285 f-LIGRLO-NH2 RT-016241 VU10010 2-Fly CHEMBL1212994 KB-81468 SR-01000147542-1 2-Furoyl-LIGRLO-amide trifluoroacetate salt, >=97% (HPLC) AC1LEM0C D0N2VN MolPort-002-722-568 VU-10010 2-f-LIGRLO-NH2 3-Amino-N-(4-chlorobenzyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide 2,2,2-trifluoroacetate BDBM50323691 FPRULFHDSFKYBV-UHFFFAOYSA-N SMR001398666 ZINC109066 2-Furoyl-Leu-Ile-Gly-Arg-Leu-Orn-NH2 trifluoroacetate salt cid_714286 MCULE-8947006791 STL227650 2fLI AKOS000282930 DTXSID30351931 NCGC00378784-01 VU0402469-1 2-fAP 3-amino-N-[(4-chlorophenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide HMS3431D09 SR-01000147542 [ Show all ]
Inchi Key	FPRULFHDSFKYBV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H16ClN3OS/c1-9-7-10(2)21-17-13(9)14(19)15(23-17)16(22)20-8-11-3-5-12(18)6-4-11/h3-7H,8,19H2,1-2H3,(H,20,22)
PubChem CID	714286
ChEMBL	CHEMBL1212994
IUPHAR	N/A
BindingDB	50323691
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
84304	Muscarinic acetylcholine receptor M4	P32211	Chrm4	Mus musculus (Mouse)	479
84305	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478

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