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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS-0421957.0001
Molecular formula	C25H34N4O4S
IUPAC name	3-[4-(2-ethoxyphenyl)piperazine-1-carbonyl]-N,N-dimethyl-4-pyrrolidin-1-ylbenzenesulfonamide
Molecular weight	486.631
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.1
Synonyms	AKOS007989816 MLS002179645 CHEMBL1592197 SMR001268675 3-[[4-(2-ethoxyphenyl)-1-piperazinyl]-oxomethyl]-N,N-dimethyl-4-(1-pyrrolidinyl)benzenesulfonamide MCULE-6447382405 BDBM68320 MolPort-005-713-898 3-[4-(2-ethoxyphenyl)piperazin-1-yl]carbonyl-N,N-dimethyl-4-pyrrolidin-1-yl-benzenesulfonamide cid_25161603 ZINC20896095 N,N-dimethyl-3-(4-o-phenetylpiperazine-1-carbonyl)-4-pyrrolidino-benzenesulfonamide 3-[4-(2-ethoxyphenyl)piperazine-1-carbonyl]-N,N-dimethyl-4-pyrrolidin-1-ylbenzenesulfonamide HMS3050M05 [ Show all ]
Inchi Key	FFZVSWSBYQHFGC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H34N4O4S/c1-4-33-24-10-6-5-9-23(24)28-15-17-29(18-16-28)25(30)21-19-20(34(31,32)26(2)3)11-12-22(21)27-13-7-8-14-27/h5-6,9-12,19H,4,7-8,13-18H2,1-3H3
PubChem CID	25161603
ChEMBL	CHEMBL1592197
IUPHAR	N/A
BindingDB	68320
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
77572	Cannabinoid receptor 1	P21554	CNR1	Homo sapiens (Human)	472
77573	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360
77571	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
77574	G-protein coupled receptor 55	Q9Y2T6	GPR55	Homo sapiens (Human)	319

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