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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL314114
Molecular formula	C22H28F3N5O
IUPAC name	N,N-dimethyl-2-[3-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]propylamino]pyridine-3-carboxamide
Molecular weight	435.495
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	4.1
Synonyms	N/A
Inchi Key	FAEPBXVYMFXGCS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28F3N5O/c1-28(2)21(31)17-7-5-10-26-20(17)27-11-6-12-29-13-15-30(16-14-29)19-9-4-3-8-18(19)22(23,24)25/h3-5,7-10H,6,11-16H2,1-2H3,(H,26,27)
PubChem CID	10574889
ChEMBL	CHEMBL314114
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
73325	Alpha-1A adrenergic receptor	O02824	ADRA1A	Oryctolagus cuniculus (Rabbit)	466
73326	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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