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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000762858
Molecular formula	C21H28ClN5
IUPAC name	N-[5-tert-butyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-N',N'-dimethylpropane-1,3-diamine
Molecular weight	385.94
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.0
Synonyms	STK596999 3-[[5-tert-butyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]propyl-dimethyl-amine cid_2035190 N-[5-tert-butyl-3-(4-chlorophenyl)-7-pyrazolo[1,5-a]pyrimidinyl]-N'',N''-dimethylpropane-1,3-diamine N-[5-tert-butyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-N',N'-dimethylpropane-1,3-diamine AC1M0V22 MCULE-8721880993 SMR000439716 N'-[5-tert-Butyl-3-(4-chloro-phenyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-N,N-dimethyl-propane-1,3-diamine ZINC2438956 F3348-0373 N-[5-tert-butyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-N'',N''-dimethyl-propane-1,3-diamine N1-(5-(tert-butyl)-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl)-N3,N3-dimethylpropane-1,3-diamine AKOS002294592 ST50782140 (3-{[5-(tert-butyl)-3-(4-chlorophenyl)(8-hydropyrazolo[1,5-a]pyrimidin-7-yl)]a mino}propyl)dimethylamine CHEMBL1524515 N'-[5-tert-butyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-N,N-dimethylpropane-1,3-diamine 896079-67-7 HMS2803I10 N-[5-tert-butyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-yl]-N'',N''-dimethylpropane-1,3-diamine SCHEMBL17717060 BDBM51877 MolPort-002-637-119 [ Show all ]
Inchi Key	DRIZMJQNTPKFOD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H28ClN5/c1-21(2,3)18-13-19(23-11-6-12-26(4)5)27-20(25-18)17(14-24-27)15-7-9-16(22)10-8-15/h7-10,13-14,23H,6,11-12H2,1-5H3
PubChem CID	2035190
ChEMBL	CHEMBL1524515
IUPHAR	N/A
BindingDB	51877
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
67030	C-C chemokine receptor type 6	P51684	CCR6	Homo sapiens (Human)	374
67031	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
67032	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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