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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL224672
Molecular formula	C18H22N4OS
IUPAC name	13-(dimethylamino)-5-(2-methylcyclohexyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
Molecular weight	342.461
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.9
Synonyms	9-Dimethylamino-3-(2-methyl-cyclohexyl)-3H-pyrido[3'',2'':4,5]thieno[3,2-d]pyrimidin-4-one BDBM50177094
Inchi Key	DJZFVYFKKWLWNN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H22N4OS/c1-11-6-4-5-7-12(11)22-10-20-15-14-13(21(2)3)8-9-19-17(14)24-16(15)18(22)23/h8-12H,4-7H2,1-3H3
PubChem CID	11515679
ChEMBL	CHEMBL224672
IUPHAR	N/A
BindingDB	50177094
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
61961	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
61963	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
61962	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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