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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1784050
Molecular formula	C19H13FN4O2S
IUPAC name	5-(3-fluoro-4-methoxyphenyl)-13-(prop-2-ynylamino)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
Molecular weight	380.397
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.2
Synonyms	BDBM50345951 SCHEMBL8245801 3-(3-Fluoro-4-methoxy-phenyl)-9-prop-2-ynylamino-3H-pyrido[3'',2'':4,5]thieno[3,2-d]pyrimidin-4-one
Inchi Key	CSZHNKILGMSWKB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H13FN4O2S/c1-3-7-21-13-6-8-22-18-15(13)16-17(27-18)19(25)24(10-23-16)11-4-5-14(26-2)12(20)9-11/h1,4-6,8-10H,7H2,2H3,(H,21,22)
PubChem CID	54585850
ChEMBL	CHEMBL1784050
IUPHAR	N/A
BindingDB	50345951
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
49906	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
49907	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
49905	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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