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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL194870
Molecular formula	C23H22F2N2O2
IUPAC name	N-[4-(3-azabicyclo[3.1.0]hexan-3-yl)but-2-ynyl]-2,2-bis(4-fluorophenyl)-2-hydroxyacetamide
Molecular weight	396.438
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.8
Synonyms	BDBM50165013 N-[4-(3-Aza-bicyclo[3.1.0]hex-3-yl)-but-2-ynyl]-2,2-bis-(4-fluoro-phenyl)-2-hydroxy-acetamide
Inchi Key	CSRMKZBLAHZGOX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H22F2N2O2/c24-20-7-3-18(4-8-20)23(29,19-5-9-21(25)10-6-19)22(28)26-11-1-2-12-27-14-16-13-17(16)15-27/h3-10,16-17,29H,11-15H2,(H,26,28)
PubChem CID	44400762
ChEMBL	CHEMBL194870
IUPHAR	N/A
BindingDB	50165013
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
49673	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
49672	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589

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