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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3622177
Molecular formula	C24H32FN3O4S
IUPAC name	2-[4-[(1R,2R)-2-[(4-ethylsulfonyl-2-fluorophenyl)methoxymethyl]cyclopropyl]piperidin-1-yl]-5-(methoxymethyl)pyrimidine
Molecular weight	477.595
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	2.8
Synonyms	SCHEMBL14247049
Inchi Key	CSGBBNSZGZUUSJ-RBBKRZOGSA-N
Inchi ID	InChI=1S/C24H32FN3O4S/c1-3-33(29,30)21-5-4-19(23(25)11-21)15-32-16-20-10-22(20)18-6-8-28(9-7-18)24-26-12-17(13-27-24)14-31-2/h4-5,11-13,18,20,22H,3,6-10,14-16H2,1-2H3/t20-,22+/m0/s1
PubChem CID	71116113
ChEMBL	CHEMBL3622177
IUPHAR	N/A
BindingDB	50122831
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
468993	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
468994	Glucose-dependent insulinotropic receptor	Q7TQP3	Gpr119	Mus musculus (Mouse)	335

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