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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000120305
Molecular formula	C20H18ClN7O2
IUPAC name	[4-[3-[(2-chlorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]piperazin-1-yl]-(furan-2-yl)methanone
Molecular weight	423.861
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	2.7
Synonyms	MolPort-000-101-819 {4-[3-(2-chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]piperazino}(2-furyl)methanone HMS2166P11 [4-[3-(2-chlorobenzyl)triazolo[4,5-d]pyrimidin-7-yl]piperazino]-(2-furyl)methanone AB00465189-08 ASN 06744932 MLS000527731 [4-[3-[(2-chlorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]piperazin-1-yl]-(furan-2-yl)methanone CHEMBL1531186 HMS3353F02 [4-[3-[(2-chlorophenyl)methyl]-7-triazolo[4,5-d]pyrimidinyl]-1-piperazinyl]-(2-furanyl)methanone AC1MLPBE BDBM61010 MLS002539019 {4-[3-(2-Chloro-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-piperazin-1-yl}-furan-2-yl-methanone cid_3224343 ZINC8680672 AKOS000760367 MCULE-2321712643 [4-[3-[(2-chlorophenyl)methyl]-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]piperazin-1-yl]-(furan-2-yl)methanone [ Show all ]
Inchi Key	CPAFRXCNUVTKJZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H18ClN7O2/c21-15-5-2-1-4-14(15)12-28-19-17(24-25-28)18(22-13-23-19)26-7-9-27(10-8-26)20(29)16-6-3-11-30-16/h1-6,11,13H,7-10,12H2
PubChem CID	3224343
ChEMBL	CHEMBL1531186
IUPHAR	N/A
BindingDB	61010
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
47172	G-protein coupled receptor 55	Q9Y2T6	GPR55	Homo sapiens (Human)	319
47174	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
47173	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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