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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	[11C]MMTP
Molecular formula	C18H16N4O2S
IUPAC name	13-(dimethylamino)-5-(4-(111C)methoxyphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
Molecular weight	351.412
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.2
Synonyms	Dimethylamino-3(4-[11C]methoxyphenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one 13-(dimethylamino)-5-[4-(11C)methoxyphenyl]-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,9,11-pentaen-6-one CHEMBL1082810 GTPL6212 D00REW
Inchi Key	COQPVKMATNFNLG-KTXUZGJCSA-N
Inchi ID	InChI=1S/C18H16N4O2S/c1-21(2)13-8-9-19-17-14(13)15-16(25-17)18(23)22(10-20-15)11-4-6-12(24-3)7-5-11/h4-10H,1-3H3/i3-1
PubChem CID	46891047
ChEMBL	CHEMBL1082810
IUPHAR	6212
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
46904	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
553467	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199

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