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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3213728
Molecular formula	C23H25ClN6O3
IUPAC name	N-[(E)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-2,6-dimorpholin-4-ylpyrimidin-4-amine
Molecular weight	468.942
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	4.0
Synonyms	MolPort-001-939-528 4,4'-{6-[(2E)-2-{[5-(4-chlorophenyl)furan-2-yl]methylidene}hydrazinyl]pyrimidine-2,4-diyl}dimorpholine MolPort-019-778-210 AKOS000656396 STK024619 BAS 00600118 [ Show all ]
Inchi Key	CKBQHMOUKQZWHR-PCLIKHOPSA-N
Inchi ID	InChI=1S/C23H25ClN6O3/c24-18-3-1-17(2-4-18)20-6-5-19(33-20)16-25-28-21-15-22(29-7-11-31-12-8-29)27-23(26-21)30-9-13-32-14-10-30/h1-6,15-16H,7-14H2,(H,26,27,28)/b25-16+
PubChem CID	9593133
ChEMBL	CHEMBL3213728
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
43888	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
43889	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353

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