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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000531878
Molecular formula	C20H25ClN4O4S2
IUPAC name	5-chloro-N-[4-(2,6-dimethylmorpholin-4-yl)sulfonylphenyl]-2-propylsulfanylpyrimidine-4-carboxamide
Molecular weight	485.014
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.4
Synonyms	cid_2983586 Z57906965 AKOS001853971 5-chloro-N-[4-(2,6-dimethylmorpholino)sulfonylphenyl]-2-(propylthio)pyrimidine-4-carboxamide 5-chloro-N-{4-[(2,6-dimethylmorpholin-4-yl)sulfonyl]phenyl}-2-(propylsulfanyl)pyrimidine-4-carboxamide SMR000136857 838811-17-9 HMS2444L04 5-chloranyl-N-[4-(2,6-dimethylmorpholin-4-yl)sulfonylphenyl]-2-propylsulfanyl-pyrimidine-4-carboxamide 5-chloro-N-[4-[(2,6-dimethyl-4-morpholinyl)sulfonyl]phenyl]-2-(propylthio)-4-pyrimidinecarboxamide AKOS016305058 MLS002548754 5-chloro-N-{4-[(2,6-dimethylmorpholin-4-yl)sulfonyl]phenyl}-2-(propylthio)pyrimidine-4-carboxamide CHEMBL1458591 STK882506 AC1MGBKL MCULE-9661318767 5-chloro-N-[4-(2,6-dimethylmorpholin-4-yl)sulfonylphenyl]-2-propylsulfanylpyrimidine-4-carboxamide 5-chloro-N-{4-[(2,6-dimethyl-4-morpholinyl)sulfonyl]phenyl}-2-(propylthio)-4-pyrimidinecarboxamide BDBM61440 MolPort-000-483-582 [ Show all ]
Inchi Key	CHNIQWINVIPUAO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H25ClN4O4S2/c1-4-9-30-20-22-10-17(21)18(24-20)19(26)23-15-5-7-16(8-6-15)31(27,28)25-11-13(2)29-14(3)12-25/h5-8,10,13-14H,4,9,11-12H2,1-3H3,(H,23,26)
PubChem CID	2983586
ChEMBL	CHEMBL1458591
IUPHAR	N/A
BindingDB	61440
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
42148	G-protein coupled receptor 55	Q9Y2T6	GPR55	Homo sapiens (Human)	319
42150	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
42149	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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