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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL236177
Molecular formula	C19H16N4O3S
IUPAC name	(5R)-14-(4-methoxyphenyl)-5-methyl-6-oxa-11-thia-3,9,14,16-tetrazatetracyclo[8.7.0.02,7.012,17]heptadeca-1,7,9,12(17),15-pentaen-13-one
Molecular weight	380.422
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.2
Synonyms	2,3-dihydro-9-(4-methoxyphenyl)-3(R)-methyl-1H-pyrimido[4'''',5'''':4'',5'']thieno[3'',2'':5,6]pyrido[3,4-b][1,4]oxazin-8(9H)-one BDBM50224407
Inchi Key	CHFHHUHLAQEBOY-SNVBAGLBSA-N
Inchi ID	InChI=1S/C19H16N4O3S/c1-10-7-20-15-13(26-10)8-21-18-14(15)16-17(27-18)19(24)23(9-22-16)11-3-5-12(25-2)6-4-11/h3-6,8-10,20H,7H2,1-2H3/t10-/m1/s1
PubChem CID	23657393
ChEMBL	CHEMBL236177
IUPHAR	N/A
BindingDB	50224407
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
41931	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
41933	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
41932	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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