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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	R-L3
Molecular formula	C25H20FN3O
IUPAC name	(3R)-5-(2-fluorophenyl)-3-(1H-indol-3-ylmethyl)-1-methyl-3H-1,4-benzodiazepin-2-one
Molecular weight	397.453
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.8
Synonyms	CTK8F0250 AKOS024457225 C13824 GTPL2595 SCHEMBL7515330 (3R)-5-(2-fluorophenyl)-3-(1H-indol-3-ylmethyl)-1-methyl-3H-1,4-benzodiazepin-2-one MolPort-023-276-531 B7142 D05GQK R-L364,373 CCK antagonist synthetic 11 J-000943 SureCN7515330 103342-82-1 CHEMBL1907717 NCGC00378686-01 AC1LCVIT BDBM82388 DTXSID90349652 RT-013477 CHEBI:34942 L-364,373 ZINC4654954 5-(2-FLUOROPHENYL)-1,3-DIHYDRO-3-(1H-INDOL-3-YLMETHYL)-1-METHYL-2H-1,4-BENZODIAZEPIN-2-ONE [ Show all ]
Inchi Key	CGBANSGENFERAT-JOCHJYFZSA-N
Inchi ID	InChI=1S/C25H20FN3O/c1-29-23-13-7-4-10-19(23)24(18-9-2-5-11-20(18)26)28-22(25(29)30)14-16-15-27-21-12-6-3-8-17(16)21/h2-13,15,22,27H,14H2,1H3/t22-/m1/s1
PubChem CID	656755
ChEMBL	CHEMBL1907717
IUPHAR	N/A
BindingDB	82388
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
41156	Cholecystokinin receptor type A	Q63931	CCKAR	Cavia porcellus (Guinea pig)	430
41155	Gastrin/cholecystokinin type B receptor	P32239	CCKBR	Homo sapiens (Human)	447

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