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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL242344
Molecular formula	C12H19N3O3
IUPAC name	2-amino-2-[5-(cyclohexylmethyl)-1-hydroxypyrazol-4-yl]acetic acid
Molecular weight	253.302
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	-0.3
Synonyms	BDBM50208757 (RS)-2-amino-(5-cyclohexylmethyl-1-hydroxy-4-pyrazolyl)acetic acid
Inchi Key	CARPBCWTCPQWEH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H19N3O3/c13-11(12(16)17)9-7-14-15(18)10(9)6-8-4-2-1-3-5-8/h7-8,11,18H,1-6,13H2,(H,16,17)
PubChem CID	16739377
ChEMBL	CHEMBL242344
IUPHAR	N/A
BindingDB	50208757
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
37460	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
37459	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
558418	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
37461	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912

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