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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL86853
Molecular formula	C25H20N8O3
IUPAC name	5-cyclopropyl-2-(2-nitrophenyl)-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,2,4-triazol-3-one
Molecular weight	480.488
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.7
Synonyms	2-(2-Nitrophenyl)-4-[[2'-(2H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]-5-cyclopropyl-2H-1,2,4-triazol-3(4H)-one BDBM50044527 SCHEMBL9141818 5-Cyclopropyl-2-(2-nitro-phenyl)-4-[2''-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one
Inchi Key	BPWHGUFERPAUEX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H20N8O3/c34-25-31(24(18-13-14-18)28-32(25)21-7-3-4-8-22(21)33(35)36)15-16-9-11-17(12-10-16)19-5-1-2-6-20(19)23-26-29-30-27-23/h1-12,18H,13-15H2,(H,26,27,29,30)
PubChem CID	14956770
ChEMBL	CHEMBL86853
IUPHAR	N/A
BindingDB	50044527
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29959	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359

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