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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1085397
Molecular formula	C26H27ClN4
IUPAC name	2-(5-chloro-1-methyl-3-phenylpyrazol-4-yl)-6-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]quinoline
Molecular weight	430.98
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	6.0
Synonyms	SCHEMBL1574924 (R)-2-(5-chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoline BDBM50319548 2-(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)-6-[2-((2R)-2-methyl-pyrrolidin-1-yl)-ethyl]-quinoline BHVLKNXTDWOMMA-GOSISDBHSA-N
Inchi Key	BHVLKNXTDWOMMA-GOSISDBHSA-N
Inchi ID	InChI=1S/C26H27ClN4/c1-18-7-6-15-31(18)16-14-19-10-12-22-21(17-19)11-13-23(28-22)24-25(29-30(2)26(24)27)20-8-4-3-5-9-20/h3-5,8-13,17-18H,6-7,14-16H2,1-2H3/t18-/m1/s1
PubChem CID	11618861
ChEMBL	CHEMBL1085397
IUPHAR	N/A
BindingDB	50319548
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
24128	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
24129	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445

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