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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL224375
Molecular formula	C18H13F3N4OS
IUPAC name	13-(dimethylamino)-5-[4-(trifluoromethyl)phenyl]-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
Molecular weight	390.384
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	4.1
Synonyms	9-dimethylamino-3-(p-trifluoromethylphenyl)-3H-5-thia-1,3,6-triazafluoren-4-one BDBM50177057 SCHEMBL8236636 9-Dimethylamino-3-(4-trifluoromethyl-phenyl)-3H-pyrido[3'',2'':4,5]thieno[3,2-d]pyrimidin-4-one
Inchi Key	BHDZUAZIRRYQON-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H13F3N4OS/c1-24(2)12-7-8-22-16-13(12)14-15(27-16)17(26)25(9-23-14)11-5-3-10(4-6-11)18(19,20)21/h3-9H,1-2H3
PubChem CID	11560185
ChEMBL	CHEMBL224375
IUPHAR	N/A
BindingDB	50177057
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23673	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
23675	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
23674	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
23676	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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