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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	DG-041
Molecular formula	C23H15Cl4FN2O3S2
IUPAC name	(E)-3-[1-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methylindol-7-yl]-N-(4,5-dichlorothiophen-2-yl)sulfonylprop-2-enamide
Molecular weight	592.302
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	7.8
Synonyms	DG041 2-PROPENAMIDE, 3-[1-[(2,4-DICHLOROPHENYL)METHYL]-5-FLUORO-3-METHYL-1H-INDOL-7-YL]-N-[(4,5-DICHLORO-2 BFBTVZNKWXWKNZ-HWKANZROSA-N SB16533 (2e)-3-[1-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methyl-1h-indol-7-yl]-n-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide CHEMBL565591 DG 041 UNII-1844425CLP 1844425CLP AKOS032962881 DTSI 3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide BRD-K33272502-001-01-2 D-000151746 SCHEMBL13750562 (2E)-3-{1-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methyl-1H-indol-7-yl}-N-[(4,5-dichlorothiophen-2-yl)sulfonyl]prop-2-enamide 2-Propenamide, 3-(1-((2,4-dichlorophenyl)methyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-((4,5-dichloro-2-thienyl)sulfonyl)-, (2E)- BDBM50303662 GTPL5822 4,5-dichloro-thiophene-2-sulfonic acid [(E)-3-[1-(2,4-dichlorophenylmethyl)-5-fluoro-3-methyl-1H-indol-7-yl]-acryloyl]amide D08QHS SCHEMBL15253854 (E)-3-[1-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methylindol-7-yl]-N-(4,5-dichlorothiophen-2-yl)sulfonylprop-2-enamide 861238-35-9 [ Show all ]
Inchi Key	BFBTVZNKWXWKNZ-HWKANZROSA-N
Inchi ID	InChI=1S/C23H15Cl4FN2O3S2/c1-12-10-30(11-14-2-4-15(24)7-18(14)25)22-13(6-16(28)8-17(12)22)3-5-20(31)29-35(32,33)21-9-19(26)23(27)34-21/h2-10H,11H2,1H3,(H,29,31)/b5-3+
PubChem CID	11296282
ChEMBL	CHEMBL565591
IUPHAR	5822
BindingDB	50303662
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
22145	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
22148	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
22149	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
22144	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
22147	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
22146	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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