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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1777817
Molecular formula	C22H28N4O4
IUPAC name	propan-2-yl (1S,5S)-3-[5-methyl-6-(2-methylpyridin-3-yl)oxypyrimidin-4-yl]oxy-8-azabicyclo[3.2.1]octane-8-carboxylate
Molecular weight	412.49
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.9
Synonyms	(1S,5S)-isopropyl 3-(5-methyl-6-(2-methylpyridin-3-yloxy)pyrimidin-4-yloxy)-8-azabicyclo[3.2.1]octane-8-carboxylate BDBM50344486
Inchi Key	BEXZFOIZBGPZMM-IRXDYDNUSA-N
Inchi ID	InChI=1S/C22H28N4O4/c1-13(2)28-22(27)26-16-7-8-17(26)11-18(10-16)29-20-14(3)21(25-12-24-20)30-19-6-5-9-23-15(19)4/h5-6,9,12-13,16-18H,7-8,10-11H2,1-4H3/t16-,17-/m0/s1
PubChem CID	54583577
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50344486
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
22028	Glucose-dependent insulinotropic receptor	Q7TQP3	Gpr119	Mus musculus (Mouse)	335
22029	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335

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