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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL286808
Molecular formula	C19H14O5
IUPAC name	(2S,3S,4R,5R)-12-oxotetracyclo[11.4.0.02,5.06,11]heptadeca-1(17),6,8,10,13,15-hexaene-3,4-dicarboxylic acid
Molecular weight	322.316
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.1
Synonyms	BDBM50284717 7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid
Inchi Key	BDGPBYUEDIIAAK-GEEKYZPCSA-N
Inchi ID	InChI=1S/C19H14O5/c20-17-11-7-3-1-5-9(11)13-14(10-6-2-4-8-12(10)17)16(19(23)24)15(13)18(21)22/h1-8,13-16H,(H,21,22)(H,23,24)/t13-,14+,15-,16+
PubChem CID	14041110
ChEMBL	CHEMBL286808
IUPHAR	N/A
BindingDB	50284717
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20905	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
20904	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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