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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL426018
Molecular formula	C20H20N4OS
IUPAC name	13-(dimethylamino)-5-(4-propylphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
Molecular weight	364.467
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.5
Synonyms	9-Dimethylamino-3-(4-propyl-phenyl)-3H-pyrido[3'',2'':4,5]thieno[3,2-d]pyrimidin-4-one BDBM50177102 SCHEMBL8243828 9-dimethylamino-3-(4-n-propylphenyl)-3H-5-thia-1,3,6-triazafluoren-4-one
Inchi Key	BDERYSXUUIVLID-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20N4OS/c1-4-5-13-6-8-14(9-7-13)24-12-22-17-16-15(23(2)3)10-11-21-19(16)26-18(17)20(24)25/h6-12H,4-5H2,1-3H3
PubChem CID	11530673
ChEMBL	CHEMBL426018
IUPHAR	N/A
BindingDB	50177102
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20859	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
20860	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
20858	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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