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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL297927
Molecular formula	C35H45N3O4S
IUPAC name	ethyl 2-[2-(3,5-dimethylphenyl)-3-[2-[4-[4-(methanesulfonamido)phenyl]butylamino]ethyl]-1H-indol-5-yl]-2-methylpropanoate
Molecular weight	603.822
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	7.0
Synonyms	BDBM50101167 2-(2-(3,5-dimethylphenyl)-3-{2-[4-(4-methanesulfonylamino-phenyl)butylamino]ethyl}-1H-indol-5yl)-2-methylpropionic acid ethyl ester SCHEMBL7908416 alpha,alpha-Dimethyl-2-(3,5-dimethylphenyl)-3-[2-[4-[4-(methylsulfonylamino)phenyl]butylamino]ethyl]-1H-indole-5-acetic acid ethyl ester 2-(2-(3,5-Dimethyl-phenyl)-3-{2-[4-(4-methanesulfonylamino-phenyl)-butylamino]-ethyl}-1H-indol-5-yl)-2-methyl-propionic acid ethyl ester 2-(2-(3,5-dimethylphenyl)-3-{2-[4-(4-methanesulfonylaminophenyl)butylamino]ethyl}-1H-indol-5-yl)-2-methylpropionic acid ethyl ester BCIRPBHKMMHSSH-UHFFFAOYSA-N 2-(2-(3,5-dimethylphenyl)-3-{2-[4-(4-methanesulfonylamino-phenyl)butylamino]ethyl}-1H-indol-5-yl)-2-methylpropionic acid ethyl ester [ Show all ]
Inchi Key	BCIRPBHKMMHSSH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C35H45N3O4S/c1-7-42-34(39)35(4,5)28-13-16-32-31(23-28)30(33(37-32)27-21-24(2)20-25(3)22-27)17-19-36-18-9-8-10-26-11-14-29(15-12-26)38-43(6,40)41/h11-16,20-23,36-38H,7-10,17-19H2,1-6H3
PubChem CID	44293054
ChEMBL	CHEMBL297927
IUPHAR	N/A
BindingDB	50101167
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20246	Gonadotropin-releasing hormone receptor	P30969	Gnrhr	Rattus norvegicus (Rat)	327

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