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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL18357252
Molecular formula	C30H29ClFNO4
IUPAC name	4-[3-[(2R)-2-[(E)-3-[3-(4-chloro-2-methylphenyl)-5-fluorophenyl]-3-hydroxyprop-1-enyl]-5-oxopyrrolidin-1-yl]propyl]benzoic acid
Molecular weight	522.013
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	5.7
Synonyms	US9540357, example 35 US9540357, example 34 BDBM202472
Inchi Key	BBTVQJNBBOHHAH-BUNSPHNPSA-N
Inchi ID	InChI=1S/C30H29ClFNO4/c1-19-15-24(31)8-11-27(19)22-16-23(18-25(32)17-22)28(34)12-9-26-10-13-29(35)33(26)14-2-3-20-4-6-21(7-5-20)30(36)37/h4-9,11-12,15-18,26,28,34H,2-3,10,13-14H2,1H3,(H,36,37)/b12-9+/t26-,28?/m0/s1
PubChem CID	124170712
ChEMBL	N/A
IUPHAR	N/A
BindingDB	202472
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557887	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
557886	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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