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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL178853
Molecular formula	C23H25NO2
IUPAC name	1-[3-[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]phenyl]ethanone
Molecular weight	347.458
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.9
Synonyms	SCHEMBL2785131 1-(3-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-phenyl)-ethanone AZWATKGVDUSMSO-MRXNPFEDSA-N 1-[3-(2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-yl)phenyl]ethanone BDBM50158590
Inchi Key	AZWATKGVDUSMSO-MRXNPFEDSA-N
Inchi ID	InChI=1S/C23H25NO2/c1-16-5-4-11-24(16)12-10-22-15-21-14-20(8-9-23(21)26-22)19-7-3-6-18(13-19)17(2)25/h3,6-9,13-16H,4-5,10-12H2,1-2H3/t16-/m1/s1
PubChem CID	9884652
ChEMBL	CHEMBL178853
IUPHAR	N/A
BindingDB	50158590
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18526	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
18527	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445

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