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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL2191405
Molecular formula	C27H34O5S
IUPAC name	methyl (Z)-7-[(1R,4S,5R)-5-[(E)-4-(1-benzothiophen-2-yl)-3-hydroxybut-1-enyl]-4-hydroxy-3,3-dimethyl-2-oxocyclopentyl]hept-5-enoate
Molecular weight	470.624
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.4
Synonyms	US9156810, (70, 71) CHEMBL3923193 BDBM184636
Inchi Key	AZBPBCFXVUVEQJ-QFWJEMMJSA-N
Inchi ID	InChI=1S/C27H34O5S/c1-27(2)25(30)21(11-6-4-5-7-13-24(29)32-3)22(26(27)31)15-14-19(28)17-20-16-18-10-8-9-12-23(18)33-20/h4,6,8-10,12,14-16,19,21-22,26,28,31H,5,7,11,13,17H2,1-3H3/b6-4-,15-14+/t19?,21-,22-,26+/m1/s1
PubChem CID	10096272
ChEMBL	CHEMBL3923193
IUPHAR	N/A
BindingDB	184636
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
459372	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
459373	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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