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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS-0437176.0001
Molecular formula	C20H18N4O
IUPAC name	4-(4-methoxyphenyl)-7-methyl-2-(4-methylphenyl)pyrazolo[3,4-d]pyridazine
Molecular weight	330.391
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.6
Synonyms	MolPort-009-014-757 4-(4-methoxyphenyl)-7-methyl-2-(4-methylphenyl)pyrazolo[3,4-d]pyridazine MCULE-2781717780 AS-938/12583062 ZINC36649131 CHEMBL1713770 4-(4-methoxyphenyl)-7-methyl-2-(p-tolyl)pyrazolo[3,4-d]pyridazine BDBM76072 cid_42600928 [ Show all ]
Inchi Key	AYBHAKOBTPNMON-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H18N4O/c1-13-4-8-16(9-5-13)24-12-18-19(23-24)14(2)21-22-20(18)15-6-10-17(25-3)11-7-15/h4-12H,1-3H3
PubChem CID	42600928
ChEMBL	CHEMBL1713770
IUPHAR	N/A
BindingDB	76072
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17292	Cannabinoid receptor 1	P21554	CNR1	Homo sapiens (Human)	472
17295	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360
17294	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
17293	G-protein coupled receptor 55	Q9Y2T6	GPR55	Homo sapiens (Human)	319

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