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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL6074126
Molecular formula	C22H26N4O3S
IUPAC name	5-[[4-[4-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]piperidin-1-yl]phenyl]methyl]-1,3-thiazolidine-2,4-dione
Molecular weight	426.535
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	2.1
Synonyms	5-{4-[4-((2R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-piperidine-1-yl]-benzyl}-thiazolidine-2,4-dione 5-[4-[4-[[(2R)-2-Hydroxy-2-(3-pyridyl)ethyl]amino]piperidino]benzyl]-2,4-thiazolidinedione AWMGTFQYJPFJJO-XJDOXCRVSA-N 5-{4-[4-((2R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-piperidin-1-yl]-benzyl}-thiazolidine-2,4-dione
Inchi Key	AWMGTFQYJPFJJO-XJDOXCRVSA-N
Inchi ID	InChI=1S/C22H26N4O3S/c27-19(16-2-1-9-23-13-16)14-24-17-7-10-26(11-8-17)18-5-3-15(4-6-18)12-20-21(28)25-22(29)30-20/h1-6,9,13,17,19-20,24,27H,7-8,10-12,14H2,(H,25,28,29)/t19-,20?/m0/s1
PubChem CID	44377536
ChEMBL	CHEMBL161950
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16158	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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