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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3358000
Molecular formula	C20H18F4N10O2
IUPAC name	2-[(3R)-4-[5-[[2-fluoro-4-(tetrazol-1-yl)phenyl]methoxy]pyrimidin-2-yl]-3-methylpiperazin-1-yl]-5-(trifluoromethyl)-1,3,4-oxadiazole
Molecular weight	506.426
Hydrogen bond acceptor	15
Hydrogen bond donor	0
XlogP	2.6
Synonyms	BDBM50103557
Inchi Key	AVUCFLHYBFWMSM-GFCCVEGCSA-N
Inchi ID	InChI=1S/C20H18F4N10O2/c1-12-9-32(19-29-28-17(36-19)20(22,23)24)4-5-33(12)18-25-7-15(8-26-18)35-10-13-2-3-14(6-16(13)21)34-11-27-30-31-34/h2-3,6-8,11-12H,4-5,9-10H2,1H3/t12-/m1/s1
PubChem CID	118722576
ChEMBL	CHEMBL3358000
IUPHAR	N/A
BindingDB	50103557
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
442257	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
442258	Glucose-dependent insulinotropic receptor	Q7TQP3	Gpr119	Mus musculus (Mouse)	335

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