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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL180089
Molecular formula	C26H23FO3
IUPAC name	(E)-3-[2-[(E)-3-[2-[(4-fluorophenyl)methoxy]-3-methylphenyl]prop-2-enyl]phenyl]prop-2-enoic acid
Molecular weight	402.465
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.4
Synonyms	BDBM50159762 (E)-3-(2-{(E)-3-[2-(4-Fluoro-benzyloxy)-3-methyl-phenyl]-allyl}-phenyl)-acrylic acid
Inchi Key	AVHQUWRUVYEDCE-BHJHLDTFSA-N
Inchi ID	InChI=1S/C26H23FO3/c1-19-6-4-10-23(26(19)30-18-20-12-15-24(27)16-13-20)11-5-9-21-7-2-3-8-22(21)14-17-25(28)29/h2-8,10-17H,9,18H2,1H3,(H,28,29)/b11-5+,17-14+
PubChem CID	44390831
ChEMBL	CHEMBL180089
IUPHAR	N/A
BindingDB	50159762
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15306	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
15304	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
15307	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
15305	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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