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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL235975
Molecular formula	C18H14N4O2S
IUPAC name	14-(4-methylphenyl)-6-oxa-11-thia-3,9,14,16-tetrazatetracyclo[8.7.0.02,7.012,17]heptadeca-1,7,9,12(17),15-pentaen-13-one
Molecular weight	350.396
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.2
Synonyms	2,3-dihydro-9-(4-methylphenyl)-1H-pyrimido[4'''',5'''':4'',5'']thieno[3'',2'':5,6]pyrido[3,4-b][1,4]oxazin-8(9H)-one BDBM50224395 SCHEMBL8238260
Inchi Key	ATPSAOLGMWJQNL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H14N4O2S/c1-10-2-4-11(5-3-10)22-9-21-15-13-14-12(24-7-6-19-14)8-20-17(13)25-16(15)18(22)23/h2-5,8-9,19H,6-7H2,1H3
PubChem CID	16659966
ChEMBL	CHEMBL235975
IUPHAR	N/A
BindingDB	50224395
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
14197	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
14198	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
14196	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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