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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1086292
Molecular formula	C24H25N3S2
IUPAC name	4-methyl-5-[6-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]quinolin-2-yl]-2-thiophen-2-yl-1,3-thiazole
Molecular weight	419.605
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	5.9
Synonyms	(R)-4-methyl-5-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinolin-2-yl)-2-(thiophen-2-yl)thiazole 60399-EP2308873A1 BDBM50319540 SCHEMBL1574313 6-{2-[(2R)-2-methylpyrrolidin-1-yl]ethyl}-2-(4-methyl-2-thien-2-yl-1,3-thiazol-5-yl)quinoline
Inchi Key	ASTAPGJBBBKTEX-MRXNPFEDSA-N
Inchi ID	InChI=1S/C24H25N3S2/c1-16-5-3-12-27(16)13-11-18-7-9-20-19(15-18)8-10-21(26-20)23-17(2)25-24(29-23)22-6-4-14-28-22/h4,6-10,14-16H,3,5,11-13H2,1-2H3/t16-/m1/s1
PubChem CID	11640354
ChEMBL	CHEMBL1086292
IUPHAR	N/A
BindingDB	50319540
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13495	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
13496	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445

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