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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL52919
Molecular formula	C23H21F3N4O2
IUPAC name	5-ethyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Molecular weight	442.442
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.5
Synonyms	BDBM50217973 N-[6-(2-Methyl-3-pyridinyloxy)-3-pyridinyl]-5-ethyl-6-(trifluoromethyl)indoline-1-carboxamide
Inchi Key	ARAFYPRUPJZLKF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H21F3N4O2/c1-3-15-11-16-8-10-30(19(16)12-18(15)23(24,25)26)22(31)29-17-6-7-21(28-13-17)32-20-5-4-9-27-14(20)2/h4-7,9,11-13H,3,8,10H2,1-2H3,(H,29,31)
PubChem CID	44298254
ChEMBL	CHEMBL52919
IUPHAR	N/A
BindingDB	50217973
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12250	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
12251	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
12249	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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