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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000529745
Molecular formula	C26H28N4O4S2
IUPAC name	ethyl 4-[2-[2-oxo-2-[[4-(4-phenylphenyl)-1,3-thiazol-2-yl]amino]ethyl]sulfanylacetyl]piperazine-1-carboxylate
Molecular weight	524.654
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.0
Synonyms	ethyl 4-(2-((2-((4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)amino)-2-oxoethyl)thio)acetyl)piperazine-1-carboxylate MolPort-003-025-774 AKOS024583476 F0558-0175 SMR000126825 4-[1-oxo-2-[[2-oxo-2-[[4-(4-phenylphenyl)-2-thiazolyl]amino]ethyl]thio]ethyl]-1-piperazinecarboxylic acid ethyl ester CHEMBL1470979 ZINC8653919 681224-07-7 ethyl 4-[2-[2-oxidanylidene-2-[[4-(4-phenylphenyl)-1,3-thiazol-2-yl]amino]ethyl]sulfanylethanoyl]piperazine-1-carboxylate Oprea1_145118 BDBM41598 HMS2242F06 SR-01000694948 4-[2-[[2-keto-2-[[4-(4-phenylphenyl)thiazol-2-yl]amino]ethyl]thio]acetyl]piperazine-1-carboxylic acid ethyl ester cid_5235407 MLS000529745-02 AC1NR6PC ethyl 4-[2-[2-oxo-2-[[4-(4-phenylphenyl)-1,3-thiazol-2-yl]amino]ethyl]sulfanylacetyl]piperazine-1-carboxylate REGID_for_CID_5235407 MCULE-2420625182 SR-01000694948-2 [ Show all ]
Inchi Key	APVKJTYNBUKNKK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H28N4O4S2/c1-2-34-26(33)30-14-12-29(13-15-30)24(32)18-35-17-23(31)28-25-27-22(16-36-25)21-10-8-20(9-11-21)19-6-4-3-5-7-19/h3-11,16H,2,12-15,17-18H2,1H3,(H,27,28,31)
PubChem CID	5235407
ChEMBL	CHEMBL1470979
IUPHAR	N/A
BindingDB	41598
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11396	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
11395	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353

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