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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL422877
Molecular formula	C31H37N3O2
IUPAC name	N-benzyl-3-[(R)-[(2S,5R)-2,5-dimethyl-4-prop-2-enylpiperazin-1-yl]-(3-hydroxyphenyl)methyl]-N-methylbenzamide
Molecular weight	483.656
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.4
Synonyms	BDBM50123657 SCHEMBL8930506 3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-hydroxy-phenyl)-methyl]-N-benzyl-N-methyl-benzamide
Inchi Key	APSQTBDUIGGKRT-FSGGQHMVSA-N
Inchi ID	InChI=1S/C31H37N3O2/c1-5-17-33-20-24(3)34(21-23(33)2)30(27-14-10-16-29(35)19-27)26-13-9-15-28(18-26)31(36)32(4)22-25-11-7-6-8-12-25/h5-16,18-19,23-24,30,35H,1,17,20-22H2,2-4H3/t23-,24+,30-/m1/s1
PubChem CID	11092088
ChEMBL	CHEMBL422877
IUPHAR	N/A
BindingDB	50123657
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11304	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
11303	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398

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