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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3358010
Molecular formula	C23H26F4N4O6S
IUPAC name	[3-(trifluoromethyl)oxetan-3-yl] (3R)-4-[5-[[2-fluoro-4-(methylsulfonylmethyl)phenyl]methoxy]pyrimidin-2-yl]-3-methylpiperazine-1-carboxylate
Molecular weight	562.537
Hydrogen bond acceptor	13
Hydrogen bond donor	0
XlogP	2.1
Synonyms	(R)-3-(trifluoromethyl)oxetan-3-yl 4-(5-(2-fluoro-4-(methylsulfonylmethyl)benzyloxy)-pyrimidin-2-yl)-3-methylpiperazine-1-carboxylate BDBM50103548 SCHEMBL1447981 APOAEXWNXLHNHP-OAHLLOKOSA-N
Inchi Key	APOAEXWNXLHNHP-OAHLLOKOSA-N
Inchi ID	InChI=1S/C23H26F4N4O6S/c1-15-10-30(21(32)37-22(13-35-14-22)23(25,26)27)5-6-31(15)20-28-8-18(9-29-20)36-11-17-4-3-16(7-19(17)24)12-38(2,33)34/h3-4,7-9,15H,5-6,10-14H2,1-2H3/t15-/m1/s1
PubChem CID	58190330
ChEMBL	CHEMBL3358010
IUPHAR	N/A
BindingDB	50103548
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
442142	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
442143	Glucose-dependent insulinotropic receptor	Q7TQP3	Gpr119	Mus musculus (Mouse)	335

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