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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL285378
Molecular formula	C26H29N3O6
IUPAC name	N-[(7R)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-2-(2,5-dioxopyrrol-1-yl)acetamide
Molecular weight	479.533
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	-1.1
Synonyms	N/A
Inchi Key	AOOJCPCEIPSLBL-OALDHVNGSA-N
Inchi ID	InChI=1S/C26H29N3O6/c30-17-4-3-15-11-18-26(34)8-7-16(27-19(31)13-29-20(32)5-6-21(29)33)24-25(26,22(15)23(17)35-24)9-10-28(18)12-14-1-2-14/h3-6,14,16,18,24,30,34H,1-2,7-13H2,(H,27,31)/t16-,18?,24?,25?,26?/m1/s1
PubChem CID	44276279
ChEMBL	CHEMBL285378
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10415	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
10413	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398
10414	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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