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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL197870
Molecular formula	C23H25FN4OS
IUPAC name	8-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-fluoro-4-methyl-3,4-dihydro-1H-quinolin-2-one
Molecular weight	424.538
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.1
Synonyms	8-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-fluoro-4-methyl-3,4-dihydro-1H-quinolin-2-one BDBM50171667
Inchi Key	AMUFJSCMOPQLMQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25FN4OS/c1-15-12-21(29)25-22-16(13-17(24)14-19(15)22)6-7-27-8-10-28(11-9-27)23-18-4-2-3-5-20(18)30-26-23/h2-5,13-15H,6-12H2,1H3,(H,25,29)
PubChem CID	44404439
ChEMBL	CHEMBL197870
IUPHAR	N/A
BindingDB	50171667
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9269	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
9270	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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