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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	FIMASARTAN
Molecular formula	C27H31N7OS
IUPAC name	2-[2-butyl-4-methyl-6-oxo-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pyrimidin-5-yl]-N,N-dimethylethanethioamide
Molecular weight	501.653
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.5
Synonyms	MolPort-027-836-696 2-[2-butyl-4-methyl-6-oxo-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pyrimidin-5-yl]-N,N-dimethylethanethioamide AX8246205 PubChem24450 5-Pyrimidineethanethioamide, 2-butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-1-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)- BR-A-657-K CTK8H8115 HY-B0780 UNII-P58222188P 2-(1-((2-(2H-Tetrazol-5-yl)-[1,1-biphenyl]-4-yl)methyl)-2-butyl-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)-N,N-dimethylethanethioamide AKOS016011331 C27H31N7OS DB09279 KS-00001F8R NCGC00390600-01 247257-48-3 BCP11616 CHEMBL1951143 Fimasartan (INN) SCHEMBL20126833 1904AB BR-A-657.K D10556 Kanarb ZINC3842872 2-n-butyl-5-dimethylaminothiocarbonylmethyl-6-methyl-3-[[2'-(1H-tetrazol-5-yl) biphenyl-4-yl]methyl]-pyrimidine-4(3H)-one AS-35179 CHEBI:136044 DTXSID80179460 L019170 P58222188P 257F483 BDBM50364573 CS-3509 Fimasartan [INN] SCHEMBL2229436 2-(1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)-N,N-dimethylethanethioamide AK120789 BR-A657 KB-220035 [ Show all ]
Inchi Key	AMEROGPZOLAFBN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H31N7OS/c1-5-6-11-24-28-18(2)23(16-25(36)33(3)4)27(35)34(24)17-19-12-14-20(15-13-19)21-9-7-8-10-22(21)26-29-31-32-30-26/h7-10,12-15H,5-6,11,16-17H2,1-4H3,(H,29,30,31,32)
PubChem CID	9870652
ChEMBL	CHEMBL1951143
IUPHAR	N/A
BindingDB	50364573
DrugBank	DB09279
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8813	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
547983	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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