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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL66811
Molecular formula	C24H19N7O2
IUPAC name	4-(furan-2-yl)-10-[(4-phenylmethoxyphenyl)methyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine
Molecular weight	437.463
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.6
Synonyms	BDBM50064699 7-(4-Benzyloxy-benzyl)-2-furan-2-yl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Inchi Key	ALPXBFYOHXHXPE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H19N7O2/c25-24-28-22-19(23-27-21(29-31(23)24)20-7-4-12-32-20)13-26-30(22)14-16-8-10-18(11-9-16)33-15-17-5-2-1-3-6-17/h1-13H,14-15H2,(H2,25,28)
PubChem CID	10812872
ChEMBL	CHEMBL66811
IUPHAR	N/A
BindingDB	50064699
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8497	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
8494	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
8495	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
8496	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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