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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL224322
Molecular formula	C21H24N4OS
IUPAC name	5-(1-adamantyl)-13-(dimethylamino)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
Molecular weight	380.51
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.3
Synonyms	9-dimethylamino-3-(1-adamantyl)-3H-5-thia-1,3,6-triazafluoren-4-one 3-Adamantan-1-yl-9-dimethylamino-3H-pyrido[3'',2'':4,5]thieno[3,2-d]pyrimidin-4-one BDBM50177068
Inchi Key	AKQCXZGTHURUGU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H24N4OS/c1-24(2)15-3-4-22-19-16(15)17-18(27-19)20(26)25(11-23-17)21-8-12-5-13(9-21)7-14(6-12)10-21/h3-4,11-14H,5-10H2,1-2H3
PubChem CID	11696595
ChEMBL	CHEMBL224322
IUPHAR	N/A
BindingDB	50177068
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7789	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
7790	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
7791	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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