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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1224147
Molecular formula	C16H14FN3O2
IUPAC name	2-[2-(4-fluorophenyl)ethoxymethyl]-3H-pyrido[2,3-d]pyrimidin-4-one
Molecular weight	299.305
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.9
Synonyms	2-((4-fluorophenethyloxy)methyl)pyrido[2,3-d]pyrimidin-4(3H)-one AJRBNFYXHNKFTP-UHFFFAOYSA-N 2-[2-(4-Fluoro-phenyl)-ethoxymethyl]-3H-pyrido[2,3-d]pyrimidin-4-one BDBM50325922 SCHEMBL1875603
Inchi Key	AJRBNFYXHNKFTP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H14FN3O2/c17-12-5-3-11(4-6-12)7-9-22-10-14-19-15-13(16(21)20-14)2-1-8-18-15/h1-6,8H,7,9-10H2,(H,18,19,20,21)
PubChem CID	135899325
ChEMBL	CHEMBL1224147
IUPHAR	N/A
BindingDB	50325922
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7157	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363
7158	Hydroxycarboxylic acid receptor 2	Q80Z39	Hcar2	Rattus norvegicus (Rat)	360
7159	Hydroxycarboxylic acid receptor 3	P49019	HCAR3	Homo sapiens (Human)	387

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