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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL365237
Molecular formula	C31H43Cl2N5O2
IUPAC name	3-amino-N-[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[1-[(2-phenylethylamino)methyl]cyclohexyl]piperazin-1-yl]propan-2-yl]propanamide
Molecular weight	588.618
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	4.3
Synonyms	BDBM50168658 3-Amino-N-((R)-1-(2,4-dichloro-benzyl)-2-oxo-2-{4-[1-(phenethylamino-methyl)-cyclohexyl]-piperazin-1-yl}-ethyl)-propionamide
Inchi Key	AJQRPIIDOYMRCS-MUUNZHRXSA-N
Inchi ID	InChI=1S/C31H43Cl2N5O2/c32-26-10-9-25(27(33)22-26)21-28(36-29(39)11-15-34)30(40)37-17-19-38(20-18-37)31(13-5-2-6-14-31)23-35-16-12-24-7-3-1-4-8-24/h1,3-4,7-10,22,28,35H,2,5-6,11-21,23,34H2,(H,36,39)/t28-/m1/s1
PubChem CID	44397281
ChEMBL	CHEMBL365237
IUPHAR	N/A
BindingDB	50168658
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7142	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
7140	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
7139	Melanocortin receptor 5	P33032	MC5R	Homo sapiens (Human)	325
7141	Melanocyte-stimulating hormone receptor	Q01726	MC1R	Homo sapiens (Human)	317

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