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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL182367
Molecular formula	C25H16ClF6NO2S
IUPAC name	2-[5-[3-(5-chloro-2-phenylmethoxyphenyl)thiophen-2-yl]pyridin-3-yl]-1,1,1,3,3,3-hexafluoropropan-2-ol
Molecular weight	543.908
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	7.1
Synonyms	BDBM50160916 2-{5-[3-(2-Benzyloxy-5-chloro-phenyl)-thiophen-2-yl]-pyridin-3-yl}-1,1,1,3,3,3-hexafluoro-propan-2-ol
Inchi Key	AJGJMWUDDSWHOG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H16ClF6NO2S/c26-18-6-7-21(35-14-15-4-2-1-3-5-15)20(11-18)19-8-9-36-22(19)16-10-17(13-33-12-16)23(34,24(27,28)29)25(30,31)32/h1-13,34H,14H2
PubChem CID	44392477
ChEMBL	CHEMBL182367
IUPHAR	N/A
BindingDB	50160916
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6892	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
6891	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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